Septic Shock | Shock (Part 8)

  • Published on Jun 12, 2019
  • For lesson 8 in our series of lessons on shock, we take a deep look at probably the most common, and often the most deadly kind of shock, septic shock.
    Septic shock is a result of a systemic infection, also known as sepsis. It is a very serious condition with a very high mortality rate and no matter what type of ICU you work in, you will come across this type of shock.
    We start off covering the basic of explaining what is septic shock. In this lesson, septic shock explained in a way that makes it easy to follow yet, maintaining a strong grasp on the concepts. We do take a very extensive deep dive in to the septic shock pathophysiology, explaining all the compents that work together to create this profound state of shock.
    We also cover the causes of septic shock, from bacterial septic shock, to viral and others. We then take a look at the septic shock symptoms and signs that you would see in your patients.
    Finally we thoroughly cover the treatment for septic shock including the latest guidelines for the 1 hour bundle from the surviving sepsis campaign.
    Please if you enjoyed this video or found it useful, hit the like button as this greatly helps our channel out!
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    For the next lesson in this series covering identifying what type of shock your patient is in, click here: **COMING SOON**
    You can also check out the playlist for this series of lesson on shock here:
    Also check out our other popular series of lessons on Hemodynamic Principals:

Comments • 153

  • Rossana Deleon
    Rossana Deleon Year ago +13

    I read the textbook but couldn't put things together until I watched the shock series. You are superb explaining these lessons. Thank you

    • S. T.
      S. T. Month ago +1

      @1412 Lishe thank you!!

    • 1412 Lishe
      1412 Lishe Month ago +1

      @S. T. cortisol has an important role in inflamination process by increasing glucose to provide for the cellular respiration (Krebs process). Because of the hypoperfusion, in the early, we have a hyperglycemia (Krebs is not work) and after that the anaerobic respiration has a chance to appear. At the end, we have hypoglycemia ( Fuel has run out ) and hyperlactatemia ( the product of anaerobic respiration) - my opinion.

    • S. T.
      S. T. 6 months ago +1

      @ICU Advantage please sir did you perhaps explain why blood sugar levels may go up or down in an other video? I would really love to see you explain it cause you're great at explaining and simplifying things so thanx anyway!

    • ICU Advantage
      ICU Advantage  Year ago +2

      This is so cool to hear! Really happy to hear they were received so well and that you found them helpful!

  • Trish Lo
    Trish Lo 8 months ago +2

    Great lectures! They've been really helpful during nursing school!

    • ICU Advantage
      ICU Advantage  7 months ago +2

      Happy to hear this and to know they've been helpful for you!

  • Pumpkinpie025
    Pumpkinpie025 2 years ago +5

    Just wrapped up your series on Shock- every video. They were awesome. For nursing students, this shows patho, etiology, diagnostic and treatment. Thanks for the clear and concise videos

    • ICU Advantage
      ICU Advantage  2 years ago +1

      Oh wow, thats so awesome Anne! I really tried to do my best to be as complete as I could be so I'm happy to hear you really liked them. Thanks so much for taking the time to leave such an awesome comment. Made my day!

  • karley delahoussaye
    karley delahoussaye 2 years ago +1

    Thank you so much for this series and all of your videos! I am a nursing student trying to pass my exams this week so I can graduate in quarantine. Your explanations are just what I need to review material in less than half the time of the recordings made during class.

    • ICU Advantage
      ICU Advantage  2 years ago +1

      So awesome to hear! I can't imagine trying to get through school in these times. I'm so glad this video was helpful for you and you'll have to let me know how the exam went!

  • Julia Nagel
    Julia Nagel 2 years ago +4

    Thank you! Writing a paper on Sepsis in canine patients and this helped break it down so easily!

  • Plus Ultra
    Plus Ultra 5 months ago +1

    Iโ€™m in a critical care paramedic course right now. Just wanted to say thanks so much for all your videos. They are saving my life!

    • Iliya Mathias
      Iliya Mathias 2 months ago

      I must appreciate Doctor Ani John on TheXvid for helping me and my husband in getting rid of Sepsis virus permanently after so many years in pain God sent you to save my family with your natural herbs and roots all thanks to you doctor you are a God sent keep saving lives sir I really appreciate all you have done for me and my family my God bless you richly sir๐Ÿ™.

    • ICU Advantage
      ICU Advantage  5 months ago

      So happy to hear this. Truly my pleasure to be able to help!

  • lalit ujjwal
    lalit ujjwal Year ago +1

    A very informative and easy to grasp session, even for the layman people like myself.

  • ana banana
    ana banana Year ago +2

    My uncle is had a ruptured intestine and in the middle of the surgery experienced septic shock, he currently has a wound vac and they are hoping to complete the surgery within 48hrs. I lost my mom earlier this year and just hope hes one of the lucky ones. Thank you for this informative video.

    • ICU Advantage
      ICU Advantage  Year ago +1

      I'm so sorry to hear about the loss of your mom Ana. My thoughts are with you, your family and most importantly for your uncle for a speedy recovery. Thank you for sharing and take care.

  • windrimondo
    windrimondo 2 years ago +2

    Iโ€™m not even a med student...and I loved this lecture. So much is going on within our body so quickly, yet, we canโ€™t see it. Nice content!

  • Rooster1984
    Rooster1984 2 years ago +1

    Simple and strait forward, thank you for your work.

    • ICU Advantage
      ICU Advantage  2 years ago +2

      Thank you so much for this comment. The processes going on with septic shock can be quite complex and we are glad that we were able to make them clear and understandable!

  • Han
    Han 6 months ago

    Eddie, I love your videos and I share them with all the nurses I orient in the ICU. However I feel some of the information in this video is not entirely accurate. Itโ€™s a common misconception that sepsis is an infection in the blood stream. Itโ€™s actually not. Sepsis is the bodyโ€™s exaggerated response to an infection that leads to a systemic chain reaction. Bacteremia and sepsis are two completely different things.

    • ICU Advantage
      ICU Advantage  6 months ago

      You are correct. Certainly bacteremia makes up a large portion of cases of sepsis, it isn't always the cause. I'll plan to clear this up in a future video I do specifically on sepsis. Thanks for the comment as well as sharing of the channel!

  • Risa Miles
    Risa Miles 2 years ago

    Hi Eddie!
    As always, your video is fun and informative.

    • ICU Advantage
      ICU Advantage  2 years ago

      Thank you Risa! ๐Ÿ™‚I really appreciate that! Good to hear that about topics that could be quite boring.

  • Yoslenn Ramos
    Yoslenn Ramos 2 years ago +1

    This helps me a lot for my next quarantine exam lol Thank you so much!

    • ICU Advantage
      ICU Advantage  2 years ago +2

      LOL! Quarantine exam! I love it (well hate it really) but glad that this was able to help you!

  • bananiz
    bananiz 2 years ago +4

    Very informative video my father just passed and this video helped me understand what happened greatly appreciated God bless

    • bananiz
      bananiz 2 years ago +2

      @ICU Advantage thank you it's been the most painful thing to happen to me to loss my father and been trying to see if if there's something I could of done to help him but seeing this video and getting knowledge on this topic I can see why his 82 year old body wouldn't be able to fight something like this off. I appreciate your thurl explanation.

    • ICU Advantage
      ICU Advantage  2 years ago +4

      I'm so sorry to hear of this and for the loss of your father! ๐Ÿ˜ข

  • Regina Roberts
    Regina Roberts 2 years ago

    Hubby survived sepsis this week. I learned this lesson but one video at a time. We caught it early-warm stage. So scary though. It started with what looked like a heart attack. Nice video. Concise and colorful!!!

    • ICU Advantage
      ICU Advantage  2 years ago

      WOW! So glad you got it early and he is ok! Glad you liked the video and thanks for the comment.

  • onestunningdude
    onestunningdude Year ago +2

    I had covid19 and it basically put me in septic shock. I was in ICU, but didnt have to use the ventilator. It was the roughest 2 weeks of my life. My D-Dimer was like at 60k. I'm so glad I went to the hospital like my wife said to do. Praise GOD I'm alive ๐Ÿ™๐Ÿพ

    • Fadou Fadouat
      Fadou Fadouat 7 months ago +1

      Hi, please if you know what's the treatment that they gave you for the septic shock can you tell me?

    • ICU Advantage
      ICU Advantage  Year ago +1

      Wow! Thank you for sharing and thanks for listening to your wife! Glad to hear you made it out the other side of all that. Take care.

  • Bekk Fawcett
    Bekk Fawcett 9 months ago +1

    these are amazing explains it so well i appreciate these lessons so much

  • Margie Ann
    Margie Ann  Year ago +7

    This was my death sentence, I have no idea how I survived this....Septic shock secondary to streptococcus pneumoniae bacteremia and pneumonia, acute hypoxemic respiratory failure, acute kidney injury, hypokalemia, thrombocytosis, and chronic normocytic anemia.

    • Marie Espinoza
      Marie Espinoza Year ago

      Were you able to recover 100% or do have lasting side effects? My loved one is recovering from sepsis but his kidneys have not started working yet. He was fighting Covid then sepsis on top of that...๐Ÿ˜ญ

    • ICU Advantage
      ICU Advantage  Year ago +1

      Wow, sounds like you went through the ringer! Glad to hear you fought through and are here with us today! So scary.

  • BlackCherry5Oh
    BlackCherry5Oh Year ago +8

    Sepsis almost killed me in July of 2017, spent 2 weeks in ICU. Had I not sought treatment when I did I have no doubt I wouldn't be here today.

    • ICU Advantage
      ICU Advantage  Year ago

      Wow! So glad that you went it got help! It gets bad and if you don't get help right away it can be very deadly!

  • Brian
    Brian Year ago +2

    I had septis - Can tell you I've never felt so ill in all my life. I vomited over and over, dripping with sweat- couldn't sit still panicking all the time. GP Doctor didn't do much came on a home visit gave me anti sickness drugs and left. I couldn't keep the tablets down due to sickness. Had to go to hospital an ambulance was called as it kept getting worse. This was all at Christmas

    • Fadou Fadouat
      Fadou Fadouat 7 months ago

      Please can you tell me how did you recover from it? Did the treatment in the hospital do anything?

    • Avengers Gaming
      Avengers Gaming Year ago

      At you safe from that casue??

  • Ogi
    Ogi 2 years ago +5

    This should really have more views. Great job!

  • Linda Buysse
    Linda Buysse Year ago

    Love this, covered it very well!

  • Carl Angelo
    Carl Angelo Year ago +1

    This was so good. Thanks so much!

  • Darlene Scott
    Darlene Scott Year ago

    Thank you for the information. I just resently got septic shock two months ago. This is the second time I got septic shock.

    • Fadou Fadouat
      Fadou Fadouat 7 months ago

      @Darlene Scott hi, I'm sorry to bother you can you tell me what happened after the septic shock like did u get any organ failure or that doesn't happen to anyone?

    • Darlene Scott
      Darlene Scott Year ago

      @ICU Advantage Oh thank you. I actually got Septic Shock, E-Coli, a UTI and a blood disease from eating metal. In March. Im not sure how I ate the metal, I had surgery to get a stent placed inside of me, I have a kidney stone stuck to me, im having surgery in 3 weeks from now. I been on 3 different kinds of antibiotics. I went home from the hospital with a pick line in my arm for IV meds. Im still in a lot of pain in my kidney. I got a infection in my stent and kidney, one of the Drs in the emergency a few weeks ago again thought I had septic shock the 3rd time.

    • ICU Advantage
      ICU Advantage  Year ago +1

      Wow, twice!?! Glad to hear you have recovered now twice. Once is more than enough for any person to have to go through.

  • Angel Nkhoma
    Angel Nkhoma 7 months ago

    Well explained ๐Ÿ‘

  • Kate Sun
    Kate Sun 3 months ago

    Very good presentation. Thank you.

  • drharini bp
    drharini bp 4 days ago

    I lost my dad in ICU 3 months back due to this septic shock

  • Geo Kouassi
    Geo Kouassi Month ago

    Thank you. Iโ€™m not in healthcare but I got it.

  • Mary Bissell
    Mary Bissell Year ago

    I am a 3rd year nursing student about to qualify and Have an assignment to complete on septic shock of a patient in my scenerio .. very helpful and easier than uni to understand. thank you. what I needed to get these assignments completed for deadline.

  • Lorraine Kavedza
    Lorraine Kavedza Year ago

    So many things become clear to me now. Thank you.

  • shelly ranae
    shelly ranae Year ago

    I developed really bad livedo Reticularis from my hips down directly after a surgery complicated by cellulitis at the navel incision wound. Had numerous testing done for conditions all the way from lupus, antiphospholipid syndrome to cryoglobulinemia yet it has yielded no answers. It worries me because it was of rapid onset with right sided peripheral edema . This was a year ago. The livedo continues to get worse. I know its hard to give any medical advice in this situation. But if you have any insights or ideas id definitely appreciate it โค๏ธ. Im wondering if shock or hypoperfusion? Thank you

  • Alaa Hussain
    Alaa Hussain Year ago

    thank you everything in this lesson was my favorite

    • Universal035
      Universal035 Year ago

      @ICU Advantage Hello, I've been diagnosed with folliculitis since 2013 caused by staphylococcus infection. I also had furnacles & fear that I may have Sepsis. I heard that this is an uncurable deadly disease & I'm afraid to die from this. I don't know what to do.

    • ICU Advantage
      ICU Advantage  Year ago

      Happy to hear this Rose!

  • AbdElrahman mohamed

    Great explanation thank u ๐Ÿ˜๐Ÿ˜๐Ÿ˜

    • nolusindiso dayile
      nolusindiso dayile 9 months ago

      I've been reading my books you are superb in explaining Neurogenic shock thank you for your work

    • ICU Advantage
      ICU Advantage  Year ago

      You are welcome ๐Ÿ˜Š

  • George Pavlik
    George Pavlik 2 months ago

    The only comment I would have to make the videos more suitable for a studying nursing student is utilizing generic names such as, norepinephrine instead of Levophed. I hear the NCLEX will only give us the generic names. But I do understand adrenaline is more common and easier to say than epinephrine. I will keep watching either way!
    I'm here because you do a fantastic job of explaining the pathophysiology, which makes the signs and symptoms make sense instead of just blindly trying to memorize a book.

    • ICU Advantage
      ICU Advantage  Month ago

      My apologies as this was an earlier video and I tend to just use the most commonly used name. I do try and cover both names, especially when doing specific med reviews, but if they are in quick mention/passing in videos I may just use the common usage here.

  • ArchieBlue
    ArchieBlue 2 years ago +1

    Last september I got pneumonia, i thought it was a cold or flu but long story short after about 2 days I was extremely sick got rushed to the hospital & hooked up into a ventilator put into a induced coma (ladted 8 days) got septic shock that same night & was told (after waking up from coma) I only had about 30% chance of surviving. the hospital called my family at about 1-2am to possibly say goodbye. Luckily I survived but I am still not fully recovered from it & I would say im in the higher risk for the cornavirus. Like i said the doctors told me if i was old or really young the 30% chance of survival would be lower then 30%, is there different types of septic shocks because you said it was 50%?

    • ArchieBlue
      ArchieBlue 2 years ago

      @ICU Advantage Oh ok fair enough that makes sense, that's still a very high chance & I'm so greatful I survived but it did change my body in some weird ways still.
      Thanks for the reply stay safe.

    • ICU Advantage
      ICU Advantage  2 years ago +1

      Honestly the survivability statistics vary so much depending who you ask. This is a generally accepted number.

  • Gen Gomez
    Gen Gomez 2 years ago

    New subscriber!๐Ÿ™‹๐Ÿ™‹๐Ÿ™‹๐Ÿ™‹
    I have a good Professor in Graduate school, but your content is amazingly simplified.โ˜บ

    • Rachuri Annapurna
      Rachuri Annapurna 10 months ago

      Very nice tq sir

    • ICU Advantage
      ICU Advantage  2 years ago

      Thank you Gen and so glad to have you aboard. Thank you for such an awesome comment. Totally humbled to hear that!

  • tammy koble
    tammy koble Year ago +1

    Have you heard of the program At East Virginia medical Hospital? They are averaging an 80-90% success rate bc they have realized that septic shock can be treated with intravenous vitamin C, steroids and thiamine (a b vitamin). This protocol is being adopted in many countries yet Americans in other parts of the country are not aware of this near miraculous discovery.

  • Tiba younis
    Tiba younis Year ago +1

    I have pathology exam so this video is really hepful great great dr

  • Prince-Moses Channel
    Prince-Moses Channel 2 years ago

    ๐Ÿ‘๐Ÿฝ๐Ÿ‘๐Ÿฝ๐Ÿ‘๐Ÿฝ๐Ÿ‘๐Ÿฝ๐Ÿ‘๐Ÿฝ๐Ÿ‘๐ŸฝFantastic lessons

  • O O
    O O 7 months ago +1

    Please can you do ARF/ARDS? Thank you

  • Nic
    Nic 4 months ago

    Hi Eddie, what is the difference between Pulmonary Oedema and ARDS, or are they essentially the same thing but from different causes? :)

    • Nic
      Nic 4 months ago

      @ICU Advantage thank you Eddie, sounds good! ๐Ÿ™

    • ICU Advantage
      ICU Advantage  4 months ago +2

      So pulmonary edema is fluid in either the alveoli and/or interstitial areas. ARDS is a complex lung disease, inflammation and damage of which pulmonary edema (primarily alveolar) is associated.
      Certainly warrants more discussion and I do have both topics on the todo list!

  • Marie Espinoza
    Marie Espinoza Year ago +1

    How long typically before the kidneys work again after acute kidney injury or do they stop working?

    • fire
      fire Year ago

      When my mother got septic shock her kidneys came back to full function in I would say 10 days with dialysis.

    • ICU Advantage
      ICU Advantage  Year ago +1

      It truly depends. Theres no clear answer to this. Sometimes they come back sometimes they don't. Sometimes it is quick, sometimes it is prolonged.

  • Sherietta Anglin
    Sherietta Anglin Year ago

    Wow my sister just had surgery a few days ago and also experienced septic shock . She had her 3rd surgery in 4 days. She also has a wound vac. Her abdominal tissue needs to be removed and stomach muscles .

  • Satwik Bhatia
    Satwik Bhatia Year ago +1

    Thankyou sir...... Love from india๐Ÿ‡ฎ๐Ÿ‡ณ๐Ÿ‡ฎ๐Ÿ‡ณ

  • MO
    MO 11 months ago +1

    How long it takes to survive a septic shock in the ICU unit ? How many days ?

    • ICU Advantage
      ICU Advantage  11 months ago +1

      Impossible to say. It depends on way too many factors. Could be days, could be months.

  • Nikki R
    Nikki R Year ago

    My fiancรฉ is in the hospital right now with sepsis, unfortunately we are unable to get information on his status but last update we had was his... BP was 129/62, HR 112, O2- 94%.
    Was told his extremities are swollen and he has fluid on his stomach. Can anyone explain these results to me? I know itโ€™s vague. He did have low grade fever yesterday, too weak for PT.

    • ICU Advantage
      ICU Advantage  Year ago +1

      Hi Nikki and so sorry to hear about your fiancรฉ and hoping for a speedy recovery for him. As for your questions, I really couldn't speak to his situation and the complexity of what may or may not be going on. My suggestion would be when you speak to the staff next time, let them know if they are saying something that you don't understand or ask them to further explain so you can understand. I think that most would be more than happy to do so and often don't realize they are talking a foreign language to people. Take care.

  • James Wright
    James Wright Year ago +1

    What software program are you using for your videos???

    • ICU Advantage
      ICU Advantage  Year ago +1

      Simple stuff actually James. Just Adobe Photoshop, screen casting to an iPad and using an Apple Pencil on there. Record part of the screen with QuickTime ๐Ÿ˜Š

  • Bailey Moran
    Bailey Moran 11 months ago

    I just went through septic shock last year. It was horrible. I was so out of it. I had no idea I was even in the hospital. Due to Covid, I sat in the ER for almost 48 hrs, apparently. I vaguely remember the ambulance. Mostly because of pics. The few memories I have are terrifying fever dreams, pain (small intestine perforation), and confusion. I woke up 13 days and 3 surgeries later. I had no use of my legs as my nervous system got damaged. I have most mobility back but still suffer nerve damage and mild issues. Iโ€™m so scared it will happen again one day!

  • patrice Leeann
    patrice Leeann Year ago

    My sister was just hospitalised on the 4/9 2021 she had septic shock she is in icu on a ventilator & receiving dialysis treatment her vital signs are currently up to normal She's always sedated because she gets very agitated due to the pain so she's never really awake .. she's 38 and fighting I'm praying for her everyday I hear nothing good about this bacteria I'm a cna in the medical field and have been learning as much as I can about this disease I'm not a Dr but I want to know my sister chances at this yet i know only God really knows but this video was very helpful. Thank you .

    • ICU Advantage
      ICU Advantage  Year ago

      I'm so sorry to hear about your sister and prayer for her and her recovery!

  • Ms Lady
    Ms Lady Year ago +1

    Thank you Mr. Watson!

  • jeff lim
    jeff lim Year ago +1

    How is septic shock diagnosed?

    • ICU Advantage
      ICU Advantage  Year ago +2

      Great question Jeff. The surviving sepsis campaign actually has a lot of great information on this. But first and foremost there must be an infection, either known or suspected. This is why we get cultures, especially blood. From there, there are several indications that would meet criteria for sepsis. Theres a lot to mention, but things like hypotension, fever, tachypnea, tachycardia, etc etc. You have to have 2 of those for sepsis. Then, for septic shock, this is the most advanced stage of severe sepsis where the hypotension persists after fluid resuscitation.

  • Eric Sangueza
    Eric Sangueza Year ago


  • Zahraa Abbas
    Zahraa Abbas 2 years ago +5

    4:15 A.M. and Iโ€™m doing a shock homework ๐Ÿ’”๐Ÿ˜‚

    • ICU Advantage
      ICU Advantage  2 years ago +3

      Yikes, that doesn't sound like a good time lol

  • roger van Bommel
    roger van Bommel Year ago

    Question, is it possible to survive septic shock/sepsis without treatment or is there certain death?

  • Reyhane
    Reyhane 2 years ago

    Thanks ๐ŸŒธ๐ŸŒธ

  • Farah Awil
    Farah Awil 2 years ago

    good job

  • Miracle Arceus
    Miracle Arceus Year ago

    i have a silly question. why is levo the first line vasopressor thats used in sepsis?

    • Dana O
      Dana O Year ago

      Great question

    • Miracle Arceus
      Miracle Arceus Year ago

      @ICU Advantage thank you so much for that explanation.

    • ICU Advantage
      ICU Advantage  Year ago +2

      Not a silly question at all. They did studies looking at the effectiveness of various vasopressors and found Levo to get the best bang for the buck, if you will. Levo is a pretty potent vasopressor with limited other effects, which probably explains that.

  • S. T.
    S. T. 6 months ago


  • Jolie Apuzzo
    Jolie Apuzzo 2 years ago +1

    So this is what killed my cat. Wish I saw this beforehand. ๐Ÿ˜ž

  • venkybly
    venkybly 2 years ago


  • Moses m
    Moses m 2 years ago


  • Bumin Khan
    Bumin Khan 2 years ago +2

    R.i.P. Mohammed Ali

    • ICU Advantage
      ICU Advantage  2 years ago +2

      Interesting info and thanks for sharing! I didn't know that was why he ended up dying.

    • ICU Advantage
      ICU Advantage  2 years ago


  • Mr. crabs frfr
    Mr. crabs frfr Year ago

    Remember how gross it was when Meg died

  • LazeeChap
    LazeeChap Year ago +2

    Watched this because of Ali

    • jeff lim
      jeff lim Year ago

      Who is ali

    • ICU Advantage
      ICU Advantage  Year ago

      2nd person to have said this! I didn't know the first time why, but now I do.

  • Shantanu Bartakke
    Shantanu Bartakke Year ago +3

    I got reasion of my mom death .

  • Tania
    Tania Year ago

    Came here after a woman died of septic shock due to an abortion pill

    • NPKRN
      NPKRN 5 months ago

      I don't think that in and of itself is possible. There had to be a infection from a germ.

    • ICU Advantage
      ICU Advantage  Year ago +1

      I'm sorry to hear that ๐Ÿ˜”

  • Brendan Kelly
    Brendan Kelly Year ago

    Make sure sorry.